This Washington Post article on standing up at work struck home for me because I recently got a motorized desk that allows me to stand up at my desk all day. The article cites experts on both sides of the debate, some in support of the health benefits of standing and others who think it's ridiculous.
Standing feels better though it's more taxing over long stretches. Until they settle the health debate, I'm standing until I can't anymore and then sitting for respite. It may seem like a hedge but it's just listening to my body.