The Second Law of Thermodynamics

I love Steven Pinker's response to the 2017 Edge Question: what scientific term or concept ought to be more widely known?

He chose the Second Law of Thermodynamics. I'm not sure that's a concept that needs more publicity, unless you consider almost all of science underrated, which is fair. It's his reason why he chose the law which is so striking:

Why the awe for the Second Law? The Second Law defines the ultimate purpose of life, mind, and human striving: to deploy energy and information to fight back the tide of entropy and carve out refuges of beneficial order. An underappreciation of the inherent tendency toward disorder, and a failure to appreciate the precious niches of order we carve out, are a major source of human folly.
To start with, the Second Law implies that misfortune may be no one’s fault. The biggest breakthrough of the scientific revolution was to nullify the intuition that the universe is saturated with purpose: that everything happens for a reason. In this primitive understanding, when bad things happen—accidents, disease, famine—someone or something must have wanted them to happen. This in turn impels people to find a defendant, demon, scapegoat, or witch to punish. Galileo and Newton replaced this cosmic morality play with a clockwork universe in which events are caused by conditions in the present, not goals for the future. The Second Law deepens that discovery: Not only does the universe not care about our desires, but in the natural course of events it will appear to thwart them, because there are so many more ways for things to go wrong than to go right. Houses burn down, ships sink, battles are lost for the want of a horseshoe nail.
Poverty, too, needs no explanation. In a world governed by entropy and evolution, it is the default state of humankind. Matter does not just arrange itself into shelter or clothing, and living things do everything they can not to become our food. What needs to be explained is wealth. Yet most discussions of poverty consist of arguments about whom to blame for it.

As Shelley once wrote:

"Round the decay
Of that colossal Wreck, boundless and bare
The lone and level sands stretch far away."